Physical Medicine Rehabilitation

Multiple sclerosis rehabilitation: from impairment to by Marcia Finlayson

By Marcia Finlayson

"This edited guide offers a entire source to notify and consultant health and wellbeing and rehabilitation practitioners as they interact within the rehabilitation strategy with a number of sclerosis sufferers. The textual content presents a broad-based point of view on a number of sclerosis, the way it affects way of life, and the techniques that may be hired via rehabilitation practitioners to permit individuals with MS to totally have interaction in everyday Read more...

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Additional info for Multiple sclerosis rehabilitation: from impairment to participation

Sample text

1 Jean Martin Charcot (1825–1893) is often credited with providing the first comprehensive description of MS. ) commonly used today for the treatment of acute MS attacks. The first medication to ­scientifically demonstrate the ability to alter the course of MS was beta interferonβ-1b (Betaseron®), which was FDA approved in 1993. Subsequent medications were intramuscular beta interferonβ-1a (Avonex®), 1996; glatiramer acetate (Copaxone®), 1996; and subcutaneous beta interferonβ-1a (Rebif®), 2002.

The relationship between the demyelination and the axonal degeneration is uncertain. Axonal damage may be a consequence of the loss of the protective myelin coating, or axonal degeneration may occur at the same time as, or before, the demyelination. Another source of support for considering MS as an autoimmune disease comes from changes in the immune system seen in people with MS. People with MS have more activated lymphocytes in their circulation and decreased suppressor function of their immune cells.

Since this initial report, many other important studies have documented the benefits of rehabilitation for people with MS. This book describes the rehabilitation assessments and interventions recommended for people with MS and evaluates the evidence examining their use. 2 Epidemiological Overview of MS Epidemiologists ask questions about patterns of health and illness in the population and their findings aid in understanding risk factors for disease, potential causal pathways, and possible directions for treatment protocols.

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