Microfluidics for Biotechnology, Second Edition by Jean Berthier

By Jean Berthier

The appliance of microfluidics to biotechnology is an exhilarating new quarter that has already all started to revolutionize how researchers examine and control macromolecules like DNA, proteins and cells in vitro and inside residing organisms. Now in a newly revised and extended moment version, the Artech condominium bestseller, "Microfluidics for Biotechnology" brings pros and scholars to the leading edge of this burgeoning box. that includes a number of updates and together with 3 fullyyt new chapters, this publication offers a close examine the mechanical habit of the differing kinds of micro/nano debris and macromolecules which are utilized in biotechnology. Engineers and laboratory researchers concerned with the notion and layout of bio-tech microdevices, in addition to graduate and post-graduate scholars in similar classes.

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Microdrop impact on liquid or solid surfaces is of great interest for ink-jet printing and spray cooling. The K number has been defined to separate the splashing and spreading regimes. 27) A high K number value indicates splashing. In microreactors, the Graetz number estimates the relative importance of diffusion and convection length. For example, in a straight channel, it compares the mean axial length traveled by a particle/molecule to the mean transverse length traveled by the particle/molecule.

Constantin, N. David, and N. Sarrut, “Micro-Extractor for Liquid-Liquid Extraction, Concentration and In Situ Detection of Lead,” IMRET-10: 10th International Conference on Microreaction, AIchE 2008 Spring National Meeting, New Orleans, LA, April 6–10, 2008. , D. Irimia, R. G. Tompkins, and M. Toner, “Continuous Inertial Focusing, Ordering, and Separation of Particles in Microchannels,” PNAS, Vol. 104, 2007, p. 1882. [25] Sudarsan, A. , and V. M. Ugaz, “Fluid Mixing in Planar Spiral Microchannels,” Lab Chip, Vol.

68) The advantage of the energy approach is that it is general. 29 Sketch of the displacement of a fluid element in a duct. 30 Bernoulli’s law: energy conservation along a streamline. P is the pressure and V is the velocity. third, friction can be accounted for, by assuming a loss of energy due to friction on the rigid wall between any two cross sections. Streamlines do not account for wall friction since they are not bounded by walls, but energy conservation in a cross section does. As we have seen before, the pressure drop caused by friction on the wall is usually expressed by DP = f 4L æ 1 2ö ç ρU ÷ Dh è 2 ø where f is the friction factor (nondimensional).

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