Medical Physiology: The Big Picture (LANGE The Big Picture) by Johnathan D. Kibble, Colby R. Halsey

By Johnathan D. Kibble, Colby R. Halsey

Get the massive photograph of scientific body structure -- and concentrate on what you actually need to grasp to ace the path and board exams!

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"This very good, no-frills method of body structure recommendations is designed to aid clinical scholars and different health and wellbeing professions scholars overview the fundamental innovations linked to body structure for the scientific occupation. the knowledge is concise, exact and timely."

If you don't have limitless research time scientific body structure: the large photo is precisely what you would like! With an emphasis on what you “need to know” as opposed to “what's great to know,” and more suitable with 450 full-color illustrations, it bargains a targeted, streamlined assessment of scientific body structure. You'll discover a succinct, easy presentation designed to make even the main advanced innovations comprehensible in a brief volume of time.

With simply the ideal stability of data to provide you the sting at examination time, this particular mixture textual content and atlas features:

• A “Big Picture” point of view on accurately what you want to comprehend to ace your path paintings and board exams
• insurance of the entire crucial parts of body structure, together with basic, Neurophysiology, Blood, Cardiovascular, Pulmonary, Renal and Acid Base, Gastrointestinal, and Reproductive
• 450 classified and defined full-color illustrations
• one hundred ninety board exam-style questions and solutions -- together with a whole perform try on the finish of the book
• detailed icon highlights very important medical details

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Hormones or neurotransmitters Depolarization Opens voltage-gated Ca2+ channels IP3 Hormones or neurotransmitters Ca2+ release from SR Open ligand-gated Ca2+ channels [Ca2+] Ca2+-calmodulin (CaM) myosin-light-chain kinase Phosphorylation of myosin light chains Myosin ATPase Myosin~P + actin Cross-bridge cycling FIGURE 1-16 Sequence of events in contraction of smooth muscle. Tension 98761_Ch01 5/7/10 6:38 PM Page 22 22 Board Review Series: Physiology ■ There is no troponin; instead, Ca2+ regulates myosin on the thick filaments.

B. Muscarinic receptors ■ ■ ■ ■ ■ ■ are located in the heart (M2 ), smooth muscle (M3 ), and glands (M3 ). , decreased heart rate, decreased conduction velocity in AV node). , increased GI motility, increased secretion). are activated by ACh and muscarine. are blocked by atropine. Mechanism of action: (1) Heart SA node: Gi protein, inhibition of adenylate cyclase, which leads to opening of K+ channels, slowing of the rate of spontaneous Phase 4 depolarization, and decreased heart rate. (2) Smooth muscle and glands: Gq protein, stimulation of phospholipase C, and increase in IP3 and intracellular [Ca2+].

Receptor types in the ANS (Table 2-2) 1. Adrenergic receptors (adrenoreceptors) a. `1 Receptors ■ ■ ■ ■ are located on vascular smooth muscle of the skin and splanchnic regions, the gastrointestinal (GI) and bladder sphincters, and the radial muscle of the iris. , contraction or constriction). are equally sensitive to norepinephrine and epinephrine. However, only norepinephrine released from adrenergic neurons is present in high enough concentrations to activate α1 receptors. Mechanism of action: Gq protein, stimulation of phospholipase C, and increase in inositol 1,4,5-triphosphate (IP3) and intracellular [Ca2+].

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