By Tibor Tot
Large-section histopathology widens your perspectives...
Correct prognosis and staging are crucial in selecting the right
therapy of colorectal carcinoma, essentially the most universal malignancies in the USA
and Europe. As scientific technological know-how keeps to improve speedily, histopathology
remains a necessary a part of analysis in so much malignant illnesses. during this period
of interdisciplinary drugs, the position of pathology has increased to supply
images that simply correlate with endoscopic, radiological, or operative
In this amazing atlas, Tibor Tot provides colon pathology in huge
histological sections, with cross-sections of complete tumors of their anatomic
environments and their circumferential surgical margins. those designated pictures
form a advisor to analysis, tumor typing and staging in response to TNM standards.
They support to evaluate the completeness of a surgical excision and to appreciate
the heterogeneity of colorectal carcinomas.
- instances illustrated in two-page spreads with medical
details, traditional histopathology, and large-section histology photographs
enlarged to nearly an entire web page.
- Pathology visible within the context of surrounding tissues
- The margins of malignant tumors seen of their
- Schematic publications to interpretation of the
- Emphasis on diagnostic merits of utilizing huge
- Technical instructions for acquiring large-section histopathology specimens
This atlas is the results of seven years of learning nearly 2,000 circumstances of colorectal
carcinoma and different intestinal lesions and is extremely suggested for
pathologists, radiologists, surgeons, and oncologists alike.
Read Online or Download Colorectal tumors: atlas of large section histopathology PDF
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Extra info for Colorectal tumors: atlas of large section histopathology
3. Practical points ¼ Taken in the plane of the deepest invasion, the large histologic section reliably demonstrates the level of primary tumor growth and allows the effects of irradiation to be assessed. 3 Rectal Carcinoma, Dukes C Fig. 3 Large-section histology image of a rectal carcinoma with lymph node metastasis. 4 Mucinous Carcinoma of the Colon Patient data: 66-year-old man with sideropenic anemia and celiac disease. A large tumor was found endoscopically in the area of the ileocecal valve.
Meticulous clinical and radiological investigations carried out in the present case ruled out the presence of another primary carcinoma. Thus, the tumor was classified as advanced colon carcinoma with obvious intratumoral heterogeneity. Fig. 13 a Fig. 13 b Practical points ¼ In this particular case, the large section included two different tumor-cell populations within the same tumor and reliably demonstrated the intratumoral heterogeneity, which allowed proper classification of the tumor. 48 Fig.
8, is a tumor that did not infiltrate beyond the level of the lamina muscularis propria, but reached the border between the muscular layer and the pericolic tissue. This is a borderline case between Dukes A or B (T2 or T3). In cases like this one, or if the infiltration is massive, examination of the specimen at different levels and serial sectioning of the paraffinembedded slices are recommended for proper staging. 8 Comparison of the Level of Invasion in Two Different Cases of Mucinous Carcinoma Fig.